Dear Subscriber,
I got a very constructive message from a reader who subscribes to another health writer, who put out information questioning C60 based on some published reports. He expressed some concern about C60, which I wrote about. I feel obliged to cover his concerns, and take the opportunity to show you how “science” is often done, and regarding malicious reports on supplements published, kind of like the “science” behind COVID and other vaccine research.
The first report I looked at was one suggesting that the C60 molecule would tie up (interfere with) DNA and RNA based on conformational analysis of theoretical interaction. What was not obvious in the title of the report was that the analysis was based on a computer simulation, NOT real time biological measurements on the real stuff. Worse, the computer simulation was based on DNA and RNA as rigid molecules with fixed parameters of measurement. DNA and RNA are NOT rigid, unless the temperature is perhaps 100 below and the molecules perfectly thermally frozen. In actuality, these molecules are like ever vibrating spring coils. Such “slinky” like coiling vibrations gives the DNA/RNA life. The computer models for this “study” seemingly were deliberately chosen and studied to conclude with a negative report.
Another report claims that C60 is a lubricant. Well, so is soy oil. I use soy oil products as an alternative to petroleum-based oil. I have used olive oil as a lubricant also.
Another report says that C60 was toxic to the kidneys of rodents and did not increase life span. If you are spooned half-truth information like this, it is easy to be confused. The C60 that was toxic to kidneys was C60 injected into the abdomen of lab rodents as AGGREGANTS. That is a totally fraudulent study to assess C60 or any substance. If you were trying to assess the safety of, say a teaspoon of salt, would you administer it as dissolved salt in water to drink, or by injections of irritating crystalline salt? Furthermore, C60 as a supplement is a solution of the molecule, not even a supplement in crystalline form or solid form, such as the vitamin C crystals or powder you might take. Any injected particulate substance can be highly inflammatory. In the case of C60, it is not soluble in water, so its aggregates will hang around the injection site indefinitely – no doubt a cause for inflammation. At least salt will dissolve.
Aluminum is a natural metal in our food supply as it is very abundant in the earth’s crust. We can handle a limited amount naturally found in food. BUT …. if injected as crystalline aluminum salts, it is a totally different and highly toxic animal. Even liquid water is toxic if inhaled. In assessing toxicity of something, we need to look at how it is given for any relevance.
An example close to my heart: The FDA tells us that ozone is a toxic gas with no known or useful medical applications. This, despite thousands of medical reports on the absolutely wondrous effects of ozone therapy, including my report on curing Ebola. Yes, ozone gas is toxic to lungs if inhaled. But not toxic if properly administered elsewhere.
C60 has been given to lab animals in a dose of 1 gm/kg with no signs of toxicity. That is 10,000 times, by body weight, what is taken by humans (0.1-0.2 mg/kg. C60 picks up the dangerous hydroxyl radical and also scavenges superoxide radicals. Terrific chemistry for protecting mitochondria.
One study said C60 did not extend the life span of mice. Well, the mice they used were already about 33 years old in human terms, and were a strain of mice bred to have fragile genes. Fair test?
I’ll close with an abstract from a recent article on C60:
Anti-Inflammatory and Antioxidant Effects of Liposoluble C60 at the Cellular, Molecular, and Whole-Animal Levels
Mizhou Hui 1, Xiaoxiao Jia 1, Xinrong Li 2, Rayko Lazcano-Silveira 1, Ming Shi 3
Affiliations expand
Free PMC
J Inflamm Res 2023 Jan 7;16:83-93.
doi: 10.2147/JIR.S386381. eCollection 2023.
article
Abstract
Introduction: Liposoluble carbon-60 (C60) has potential applications in many fields, including cosmetics, medical devices, and medicine, but its specific mechanism of action remains unclear. This study explored whether liposoluble C60 could be delivered to human organs, tissues, and cells through blood, extracellular fluid, and cell culture fluid and whether it exerts anti-inflammatory and antioxidant effects at the molecular, cellular, and whole-animal levels.
Methods: At the cellular level, we mixed C60 dissolved in grape seed oil with cell culture medium containing 10% serum and investigated its effects on tumor necrosis factor-α (TNF-α) release, migration, phagocytosis, respiratory burst, and apoptosis in freshly isolated human neutrophils. At the molecular level, we mixed a trace amount of C60 dissolved in grape seed oil with aqueous and ethanolic solutions and studied its antioxidant effect. At the animal level, we investigated the inhibitory effect of C60 on the serum inflammatory marker C-reactive protein (CRP) in beagle dogs after oral administration of C60 dissolved in grape seed oil.
Results: The results showed that the trace amount of C60 dissolved in grape seed oil significantly inhibited TNF-α release, cell migration, phagocytosis, and respiratory burst in freshly isolated human neutrophils. In addition, the trace amount of C60 dissolved in grape seed oil had a significant scavenging effect on superoxide free radicals and 1,1-diphenyl-2-trinitrophenylhydrazine free radicals. Oral administration of C60 dissolved in grape seed oil markedly reduced the level of the serum inflammatory marker CRP in beagle dogs.
Conclusion: In summary, a trace amount of hydrophobic C60 in hydrophilic media effectively produced anti-inflammatory and antioxidant effects in cells and animals. C60 dissolved in grape seed oil is a novel anti-inflammatory and antioxidant drug candidate.
Keywords: C-reactive protein; Carbon 60; anti-inflammation; anti-oxidation.
I happen to like very much what I see in this article. I did a simply search on pubmed.com for C60 to find it. There are many others.
I am very grateful to the subscriber who provided me the concerning information in C60, which spurred me to look deeper.
It made me wonder the motivating reasons behind funding worthless “studies” of no relevance. Sort of like Pharma studying the safety of vaccines by using vaccine adjuvants as “placebo.” Terri and I are continuing to take C60, and I feel further bolstered in so doing by looking at the “concerning” reports.
To Your Excellent Health,
Robert Jay Rowen, MD
PS. If you have interest in C60, this is the information on getting it I put in my report on it:
The website for C60 Purple Power is:
https://shopc60.com
Using the coupon code TBS10 gets a significant discount only on the company site. C60 is also good for pets and the coupon code will work for pet products as well.
As always, Doc, good info. Computer models should never be considered proof of anything; they are "what if" scenarios with no firm basis in science... GIGO. And we should all know that a devious lab tech can design a study to give a specific result, whether such result represents truth or not.
One correction, however, aluminum is not by any means organic, or safe. There is no free aluminum in the earth's crust, only the bauxite from which aluminum can be refined. The only "advantage" if you will, is that aluminum can be excreted more easily than heavy metals or iron.