More Juicy Tidbits from Dr. Kenner, this time on Plasmalogens, a Possible Treatment for Neurological Degeneration
September 25, 2023 Kenner Rowen Report
Dear Subscriber,
We have gotten many compliments on Dr. Kenner’s information shorts, so I will be continuing them. Here is an excellent summary of plasmalogens, which might be the discovery of the century in neurodegenerative diseases.
Please also know that I will be preparing a report on the similarities of 9/11, and what we were told, and the COVID pandemic, and what we were told. You might just be even more shocked at “your government”, with a lesson, literally, to discard and not believe anything you are told by what will be clearly be seen as evil manifest in those we have entrusted with our lives. I attended an incredible presentation by architect Richard Gates at the Menlo Park Forum on Saturday. What he presented regarding 9/11 was incredible enough. But the parallels to COVID were astounding. Please stay tuned.
To Your Excellent Health,
Robert Jay Rowen, MD
Fron Dr. Kenner:
Just For More Fun: More Bits and Pieces
Brain Nutrient and Cognitive Decline
Plasmalogens are a type of phospholipid present in almost all tissues in
humans but are most abundant in the brain and heart. They are essential for their critical role in memory, focus, and other cognitive functions. Plasmalogens constitute as much as 20% of the total phospholipids in cell membranes, especially brain, heart, and immune cells. They also function as antioxidants in parts of the body where there is a high level of oxidation. Plasmalogen deficiency can be demonstrated in various neurodegenerative disorders, such as Alzheimer’s disease (AD) and Parkinson’s disease.
It was first discovered in 1995 that a decreased level of plasmalogens in the brain is associated with Alzheimer’s disease. Levels of plasmalogens have been reported to be reduced from aging in general and are reported to be significantly reduced among Alzheimer’s patients. One study showed that there was no cognitive decline among Alzheimer’s disease participants with normal plasmalogen levels while participants with mild, moderate, or severe plasmalogen depletion had significant cognitive decline.
A deficiency of plasmalogens in AD brains might be a consequence of
reduced synthesis, oxidative stress, inflammation, and homeostatic conversion to other phospholipids to compensate for membrane deficits.
Plasmalogens have been shown to improve neurodegenerative pathology and cognitive function. It is suggested that orally administered plasmalogens can also alleviate negative mood states and sleep problems, as well as enhance mental concentration.
Goodenowe D, Cook L, Liu J, et al. Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia, Journal of Lipid Research 2007; 48(11): 2485-2498.
doi: 10.1194/jlr.P700023-JLR200, Epub 2007 Jul 30, PMID: 17664527;
Hossain M, Mawatari S, Fujino T. Plasmalogens inhibit neuroinflammation and promote cognitive function, Brain Research Bulletin 2023; 192: 56-61.
At https://doi.org/10.1016/j.brainresbull.2022.11.005
Wood P, Mankidy R, Ritchie S, et al. Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients, Journal of Psychiatry & Neuroscience 2010; 35(1): 59-62
At https://doi.org/10.1503/jpn.090059
Fujino M, Fukuda J, Isogai H, et al. Orally Administered Plasmalogens Alleviate Negative Mood States and Enhance Mental Concentration: A Randomized, Double-Blind, Placebo-Controlled Trial, Frontiers in Cell Developmental Biology 2022; vol. 10.
At https://doi.org/10.3389/fcell.2022.894734
Vitamin K and Lung Health
Vitamin K is a crucial nutrient known for its role in blood clotting and wound healing, but recent research on its involvement in lung health shows that vitamin K deficiency contributes to poor lung function, especially in people suffering from respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). A study was carried recruiting 4,092 participants aged between 24 and 77 years who underwent comprehensive lung function testing known as spirometry, provided blood samples, and completed health and lifestyle questionnaires.
Dr. Torkil Jespersen, lead researcher, highlighted the significance of these findings: “We already know that vitamin K has an important role in the blood, and research is beginning to show that it’s also important in heart and bone health, but there’s been very little research looking at vitamin K and the lungs. To our knowledge, this is the first study on vitamin K and lung function in a large general population. Our results suggest that vitamin K could play a part in keeping our lungs healthy.”
Jespersen T, Kampmann F, Dantoft T, et al. The association of vitamin K status with lung function and disease in a general population. ERJ Open Research 2023; 9:00208-2023.
doi: 10.1183/23120541.00208-2023. Epub ahead of print. PMID: 37588689; PMCID: PMC10423920.
Combining Caffeine and Taurine to Improve Cognitive Performance
Combining caffeine and taurine has synergistic effects on physical and cognitive performance. Twenty elite male boxer athletes were recruited in a study in which the researchers measured various parameters related to anaerobic power, balance, agility, and cognitive performance. Cognitive performance was evaluated using the Stroop test, which is a well-known neuropsychological test. The Wingate Anaerobic Test, which measures maximal anaerobic power, was performed as well as blood lactate levels, a measurement of perceived exertion, balance, and agility. The participants were randomly assigned to different supplement groups in a double-blind, crossover design. The groups consisted of: caffeine (6 mg/kg), taurine (3 g single dose), a combination of caffeine and taurine, and a placebo (300 mg maltodextrin). The findings clearly indicate that the mixture of caffeine and taurine have positive effects upon human mental performance and mood. The combined intake of caffeine and taurine also improved the boxers’ balance and agility. When comparing the combined intake of caffeine and taurine to taking them separately, there were differences in power output and other performance measures. This suggests that combining caffeine and taurine may have a synergistic effect and be more effective than taking them individually.
Seidl R, Peyrl A, Nicham R, Hauser E. A taurine and caffeine-containing drink stimulates cognitive performance and well-being. Amino Acids 2000; 19(3-4): 635-42.
doi: 10.1007/s007260070013. PMID: 11140366.
NAD: More Brain Food
Declining nicotinamide adenine dinucleotide (NAD+) concentration in the brain during aging contributes to metabolic and cellular dysfunction and is implicated in the pathogenesis of aging-associated neurological disorders. A randomized, placebo-controlled crossover trial study of oral nicotinamide riboside (NR) supplementation (500 mg, 2x /day, 6 weeks) in 22 healthy older adults showed that oral NR supplementation increases NAD+ levels in neuronal extracellular vesicles (NEVs) in the brain, and decreases NEV levels of insulin resistance and neuroinflammatory pathways. NR is converted into nicotinamide adenine dinucleotide (NAD+), which is critical to cellular repair and the repair of damaged DNA. As we age, we gradually lose NAD+, and this loss is linked to obesity and negative lifestyle habits like smoking. NR boosts the levels of NAD+ in the blood, and in the initial study, lowered blood pressure. Nicotinamide has been shown to prevent and reverse injury of neuronal cells. Nicotinamide can support DNA stability and can maintain membrane integrity. It can also prevent vascular clot formation.
Maiese K, Chong Z. Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain. Trends in Pharmacological Sciences 2003; 24:228–232.
doi: 10.1016/S0165-6147(03)00078-6.
Ozan M, Buzdagli Y, Evipinar C, et al. Nicotinamide Diamide and Brain Function, Nutrients 2022; 14(20), 4399.
https://doi.org/10.3390/nu14204399
Vreones M, Mustapic, Moaddel R, et al. Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin, Aging Cell 2023; 22.
e13754. https://doi.org/10.1111/acel.13754
The Green Mediterranean/High Polyphenols Diet
A modified Mediterranean diet called the “Green Mediterranean/High Polyphenols Diet” has been found to be twice as good as the classic Mediterranean Diet, promoting dramatic unstiffening of the aorta compared with the other Mediterranean diets. The aorta is the largest artery of the body and carries oxygenated blood from the heart to the periphery. This study is the first time that scientists have presented a powerful, potent effect of diet on age-related proximal aortic stiffness (PAS); reduced stiffness of the aorta is a predictor of lower risk of cardiovascular disease. The Green Mediterranean/High Polyphenols Diet is even better for protecting the heart and other vital organs.
Polyphenols are naturally occurring compounds found mostly in fruits like grapes, apples, pears, cherries and berries along with vegetables, cereals and beverages, such as coffee and green tea. Resveratrol, found in red grapes and other fruits, is a well-known polyphenol. Dietary polyphenols can significantly improve various aspects of human health. Polyphenols protect the body’s tissues against oxidative stress and associated pathologies such as cancers, coronary heart disease and inflammation.
Hoffmann A, Meir A, Hagemann T, et al. A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial, Metabolism 2023; 08. 145:155594. PMID: 37236302
Green Tea and the Prostate
We all grow cancer seeds, but they seldom grow into full-blown malignant tumors. It depends on internal conditions. In a post-mortem study of Japanese men, men who had causes of death other than cancer were found to have numerous cancer seeds in the prostate area. American men had similar numbers but a much higher rate of prostate cancer (PC). This difference has been attributed to the Japanese diet, but especially the cultural habit of drinking green tea, often throughout the day. There are other factors, such as the daily ingestion of sea vegetable stock and its high iodine levels. But the green tea drinking has been ubiquitous.
Numerous studies have revealed the molecular mechanisms of the anti-cancer effects of green tea extracts. Current knowledge regarding the anti-cancer effects of green tea extracts in the prevention and treatment of prostate cancer include several molecular mechanisms of action. These include apoptosis, androgen receptor signaling, cell cycle, and various malignant behaviors.
A meta-analysis indicated that the consumption of green tea might have a protective effect on PC in Asian populations, especially in Chinese populations. The rate of PC indicated a borderline significant association in Asian populations at the highest level of green tea consumption compared to the no/lowest level of consumption (OR = 0.62, 95% CI: 0.38, 1.01). According to this study, black tea consumption did not show a similar protective effect on PC.
Serum prostate-specific antigen (PSA) levels and PSA density (serum PSA level divided by tumor volume) values in the EGCG-treated mice were significantly lower than those in control mice.
Green tea constituents are known to affect the regulation of the cell cycle and cell cycle-related molecules in many types of malignancies.
There are too many to list here, but green tea constituents have been shown to have a beneficial influence on other mechanisms including the cell cycle, the androgen receptors, matrix metalloproteases, insulin-like growth factors, nuclear Factor‑κB, an important intracellular factor, among others.
Miyata Y, Shida Y, Hakariya T, Sakai H. Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer, Molecules 2019; 24(1):193.
doi: 10.3390/molecules24010193. PMID: 30621039; PMCID: PMC6337309.
Zheng J, Yang B, Huang T, Yu Y, Yang J, Li D. Green tea and black tea consumption and prostate cancer risk: An exploratory meta-analysis of observational studies, Nutrition and Cancer 2011; 63:663–672.
doi: 10.1080/01635581.2011.570895.
Chuu C, Chen R, Kokontis, Hiipakka R, Liao S. Suppression of androgen receptor signaling and prostate specific antigen expression by (-)-epigallocatechin-3-gallate in different progression stages of LNCaP prostate cancer cells Cancer Letters, 2009; 275:86–92.
doi: 10.1016/j.canlet.2008.10.001.
Shirakami Y, Shimizu M. Possible mechanisms of green tea and its constituents against cancer. Molecules, 2018; 23:2284.
doi: 10.3390/molecules23092284.
Hey Doc, the guy's name is Richard Gage, not Gates. He is the founder of AE911Truth.org and now presents information regarding the obvious parallels between the 9/11/01 fiction and the Covid19 bio-security-state lie.
Awesome!!! Keep'em coming😉🙏👏👏